More than two decades of Apc modeling in rodents
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چکیده
منابع مشابه
More than two decades of Apc modeling in rodents.
Mutation of tumor suppressor gene adenomatous polyposis coli (APC) is an initiating step in most colon cancers. This review summarizes Apc models in mice and rats, with particular concentration on those most recently developed, phenotypic variation among different models, and genotype/phenotype correlations.
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
سال: 2013
ISSN: 0304-419X
DOI: 10.1016/j.bbcan.2013.01.001